Item
|
Specifications
|
Appearance
|
White lyophilized powder
|
Purification method
|
The liquid phase layer analysis
|
Identification
|
The sample retention time conformed to that of standard sample
|
Purity
|
98% min
|
Water
|
≤3.0%
|
The colony counting
|
Undetectable
|
Sterility
|
BP
|
Bacterial endotoxins
|
≤ 5.0IU/ mg
|
Lr3IGF-1 (Long R3 Insulin-like Growth Factor-I or Long R3IGF-I) is an 83 amino acid analog of human IGF-I actually comprising the complete human IGF-1 sequence but with the substitution of an Arg for the Glu at position 3, as well as a 13 amino acid extension peptide at the N-terminus. This makes Long R3IGF-I significantly more potent (2-3x) than IGF-I in studies, because it has a lower affinity to be rendered inactive by IGF binding proteins, and consequently more potential activity in the body.
|